Apply daily. As nails respond, decrease application. Once nails have improved, return to Formula 2 until desired results are achieved. Formula 2 Plus may be worn alone or with color polish. The nail protein is designed for one coat to be applied over the previous. Remove as needed (usually weekly) with a non-acetone remover and start again. It is important to wash hands/nails with soap and water to remove any residue. Be sure the nail surface is completely dry before the base coat is applied. If wearing color polish, apply the nail protein as a base coat followed by color. A second coat can then be applied the following day.